Significance of quality control and quality assurance in pharmaceutical production

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Dr Md Anawar Hossain What is quality control (QC)? The main job of quality control is to test, analyse and verify the medicine at different stages of production in the pharmaceutical industry, and make sure that every product maintains the highest quality. Quality control also checks any defects in products and solve these problems using …

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Pharmacological role of Andrographolide to ameliorate inflammatory diseases and cancers

Perspectives / By

Dr Md Anawar Hossain Andrographolide has shown demonstrated therapeutic effect in inflammatory diseases, including liver diseases, joint diseases, respiratory system diseases, nervous system diseases, heart diseases, inflammatory bowel diseases, and inflammatory skin diseases. It also showed promising results in colorectal, liver, gastric, breast, prostate, lung, and oral cancers. Source of Andrographolide It is a well-known …

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Continuous direct compression process for low dose active ingredients in a solid dosage form

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Dr Md Anawar Hossain Continuous direct compression (CDC) can be a more suitable process to manufacture low-dose tablets. In addition, manufacturing by using a universal platform formulation seems to be a feasible way for producing low-dose products. Introduction Manufacturing low-dose solid dosage form encounters some challenging issues, because a homogenous distribution of active pharmaceutical ingredient …

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Prediction of product quality by using big data in pharmaceutical manufacturing

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Dr Md Anawar Hossain Analysis of big data collected from the different steps of medicine manufacturing processes for long time helps the pharma industry to find alternative ways to determine their product quality. New innovation in pharmaceutical industry In the field of pharmaceutical industry, researchers are always doing their best efforts for making new innovation, …

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Multimodal molecular imaging in medical monitoring, diagnosis, and treatment

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Dr Md Anawar Hossain Molecular imaging Molecular imaging is a powerful interdisciplinary imaging technology that performs the in vivo imaging and describes the molecular biology of human body organs (Wu and Shu, 2018). This technique can depict and elucidate living biological processes at the tissue, cellular and molecular level in a non-invasive manner. It can also …

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Quality, ratio and adverse reactions of inactive ingredients/excipients in medicine

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Dr Md Anawar Hossain Excipients and their uses in medicines All other materials except active pharmaceutical ingredient in medicines are called pharmaceutical excipients or inactive ingredients (Haywood and Glass, 2011). Excipients are considered as inactive ingredients or inert materials, however, studies over the past years indicated the adverse reactions from them. Appropriate drug delivery system …

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Innovations in clinical trial designs for a new drug development

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Dr Md Anawar Hossain A new drug development and delivering to the patients include a lot of research and many steps including R&D, clinical trials and regulatory approval, which spend millions to billions of dollars. Even after approval, it needs further expenses for market feedback and studies. Sometimes, some medicines do not get regulatory approval …

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Dual benefits of cardiovascular therapeutics for cardiovascular disease and anxiety treatment

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Dr Md Anawar Hossain The cardiovascular disorders, hypertension, coronary artery disease, and mental disturbances, such as anxiety and depressive disorders are the most common problems among the people, which are causing the high rate of morbidity and death. Anxiety and depression deteriorate the cardiovascular disease and pathologies. On the other hand, the cardiovascular diseases may …

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Thermott tool to determine protein–ligand binding constant

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Thermott is a web application for analysis of thermal shift assay (TSA)/ differential scanning fluorimetry (DSF) data (Gedgaudas et al., 2022). It is an online tool to determine the protein–compound binding constant from thermal shift data. It is a free, user-friendly and open-source online analysis software that provides estimates of the thermodynamic data on target proteins. …

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